The androgen levels, FG Score and alopecia was significantly increased in presence of wild allele than variant allele suggesting that CYP19 variant alleles imparts a protective role in ovary as well as on symptoms of hyperandrogenism, a feature milieu of PCOS, thus indicating that wild allele may be involved in endocrine abnormalities in Kashmiri women with PCOS. The gene discussed is CYP19A1; the disease is alopecia.