For example, the expression of the protein Adenosine deaminases acting on RNA 1 (ADAR1), which has dsRBD motifs, is increased in various cancers such as breast, colon, oesophagus, and etc. A recent study by SUN and colleagues showed that the expression of ADAR1 in pancreatic cancer was significantly higher than normal tissues25. Here, ADAR is linked to familial pancreatic carcinoma.