Radiological tumor responses after chemotherapy (median 3 cycles) subsequent to ITPP administration (median 94d after last ITPP dose, individual patient data follow up data are provided in Supplementary Table 3) were available for 20 (RECIST: 6 PD, 12 SD and 2 partial response (PR), Fig. 2c) and 15 patients (EORTC: 4 PMD, 7 SMD and 4 PMR, Fig. 2d), respectively. This evidence concerns the gene TPP1 and neoplasm.