Of note, elevated ERG protein expression in recurrent patients (Fig. 5A) mirrored gene expression data from two public datasets (GEO GSE32269 [62] and GSE74685 [61], Fig. S10F, G, respectively), whereby ERG over-expression has been shown to parallel the genomic fusion and to contribute to PCa progression by WNT and MAPK signaling activation [61]. This evidence concerns the gene ERG and posterior cortical atrophy.