Interestingly, among the differentially expressed antigens found by us, IL-6 has already been described as a tumor-discriminating antigen in PCa [70], while high levels of PD-L1, Integrin-β5 and Survivin upregulation seems to correlate with cancer survival and aggressiveness [50, 51, 71, 72]. This evidence concerns the gene CD274 and posterior cortical atrophy.