APC and neoplasm: Tumor primary tissue from P14 harbored a missense mutation of PIK3CA (chr3_ 178936092_A_G), an APC stop-gain mutation (chr5_112175426_G_T), a KRAS missense mutation (chr12_25398282_C_A) and a TP53 stop-gain mutation (chr17_7578263_C_T).