GPT and Decreased total neutrophil count: Significant AEs, among those rated grade 3 and higher, included febrile neutropenia (RR=2.84), neutropenia (RR=1.67), white blood cell decreased (RR=3.09), diarrhea (RR=3.74), elevated ALT (RR=0.38), nausea (RR=3.60), and vomiting (RR=1.46) (Table 1).