Because B. thailandensisvgrG5ΔCTD was not efficiently cleared from Casp8/Ripk3/Casp1/11−/− BMDMs (Fig. 3D), we hypothesized that Casp8/Ripk3/Casp1/11−/− mice may be more susceptible to infection than WT mice. This evidence concerns the gene CASP1 and infection.