C3 and age-related macular degeneration: The following 10 susceptibility SNPs associated with AMD were sequenced (human genome variation society nomenclature stated in Section 2): CFH region: rs800292; rs1061170; rs10737680; rs1329428 (Fritsche et al., 2016; Raychaudhuri et al., 2011); CFI region: rs17440077; rs4698775; rs2285714 (Chen et al., 2010; Fagerness et al., 2009; Fritsche et al., 2016); CFB region: rs429608 (Shuai et al., 2017); ARMS2 region: rs10490924 (Rivera et al., 2005); and C3 region: rs2230199 (Maller et al., 2007).