Our results revealed that the cell populations in pulmonary endarterectomized tissues include fibroblast/smooth muscle cell, T cell/natural killer (NK) cell, macrophage, cysteine rich secretory protein LCCL domain containing 2 (CRISPLD2)+ cell, cancer stem cell, mast cell, endothelial cell, and undefined. The gene discussed is CRISPLD2; the disease is cancer.