Specific cancer stem cell marker genes are CTNNB1 and TP53. CTNNB1 expression is elevated in lung tissues from patients with idiopathic pulmonary arterial hypertension and CTNNB1 is involved in vascular remodeling via the Wnt/β-catenin pathway [37]. The gene discussed is TP53; the disease is idiopathic pulmonary arterial hypertension.