Tauopathies are a subclass of neurodegenerative diseases characterizedby an accumulation of microtubule binding tau fibrils in brain regions.Diseases such as Alzheimer’s (AD), chronic traumatic encephalopathy(CTE), Pick’s disease (PiD), and corticobasal degeneration(CBD) belong to this subclass. This evidence concerns the gene MAPT and Alzheimer disease.