IL10 and neoplasm: In addition, IL-10 influences the expression of MHC class II molecules and CD86/CD80 in antigen-presenting cells (Mittal and Roche 2015), the expression of MHC class I molecules in tumor cells (Salazar-Onfray et al. 1997), the expression of costimulatory molecules on dendritic cells and regulates the IL-12 production (Rahim et al. 2005).