CKB and heart failure: Fourth, we only focused on major vascular events and major coronary events while did not test the association for other vascular diseases such as atrial fibrillation and heart failure in the present study, which have been demonstrated to be associated with improved oral hygiene care.41 Fifth, we haven’t assessed the associations for the number of teeth, the periodontal status and dental plaque without related information in CKB, which are important measurements for oral hygiene.