The Hippo pathway is directly regulated by the transcription regulator YAP.[27] Previous reports indicated that YAP signaling impacts the development of drug resistance to various cancer therapies.[28, 29] We conducted RNA‐seq‐based transcriptome profiling of KRAS G12C inhibition sensitive NSCLC (NCI‐H358) cells treated with vehicle control, AMG510, IN10018, or the AMG510–IN10018 combination for 24 h. This evidence concerns the gene KRAS and non-small cell lung carcinoma.