Similarly, regulation of other genes located centromeric to D4Z4 may be also be affected, with mouse models over‐expressing Frg1 (Gabellini et al, 2006), Slc25a4 (Ant1) (preprint: Wang et al, 2020) or null mutations in Fat1 (Caruso et al, 2013) developing muscular dystrophic phenotypes with some similarities to FSHD. This evidence concerns the gene FAT1 and facioscapulohumeral muscular dystrophy.