Indeed, SLC9A3 has been found downregulated in patients with ulcerative colitis (colon inflammation) (Fonseca-Camarillo and Yamamoto-Furusho 2012) and its loss of function has been linked to diarrhoea disorders (Dimitrov et al. 2019; Janecke et al. 2016). The gene discussed is SLC9A3; the disease is ulcerative colitis.