VEGFA and head and neck neoplasm: In fact, mutations that lead to the alterationof gene expression level of cytokines, enzymes, and growth factorsare the main responsible of tumorigenesis.31 The deregulation of the vascular endothelial growth factor-A (VEGF-A)was observed to be among the tumor promoting factors in SCC-25 cells.Indeed, VEGF-A is relatively overexpressed in SCC-25 cells comparedto the level in normal cells (Figure 3E) and constitute a promising molecular therapeutictarget for head and neck tumors.