Salivary albumin is regarded as a serum ultrafiltrate to the mouth, and it may diffuse into the mucosal secretions.Hormonal balance, nutrition, and osmotic pressure regulate albumin synthesis.High concentrations of salivary albumin have been detected in a medically compromised condition, such as immunosuppression and DM.Both normal and raised salivary albumin levels have been seen in periodontitis[ 16- 17]. Here, ALB is linked to periodontitis.