The higher the expression level of METTL3, WTAP, RBM15, RBM15B, YTHDF1, YTHDF2, HNRNPC, IGF2BP1, VIRMA, HNRNPA2B1, and IGF2BP3, the more features of tumor LUAD stem cells and the lower the tumor LUAD differentiation. The gene discussed is VIRMA; the disease is neoplasm.