LAMB2 and Hepatic fibrosis: While diverse serum indicators (e.g., type III precollagen, type IV collagen, laminin, and hyaluronidase levels), non-invasive examinations (e.g., TE), and models (e.g., the GPR, APRI, and FIB-4 index) are used for the diagnosis of liver fibrosis, few studies have been carried out on the diagnosis of significant liver inflammation in chronic liver disease.