Compared to the PMV patients with weaning failure, those with weaning success had fewer pulmonary co-rmorbidites, fewer pulmonary causes and more post-operative causes of respiratory failure, lower APACHE II score both at ICU admission and RCC transfer, a lower incidence of septic shock at ICU admission, lower creatinine level and higher platelet, hemoglobin, and albumin level at RCC transfer. The gene discussed is ALB; the disease is respiratory failure.