ACE2 and COVID-19: A study analyzing the transcriptomics of renal cells in patients with COVID-19 (28) also demonstrates that the cytopathic virus effect may occur directly in proximal tubular cells and podocytes, therefore contributing to the onset of the disease through hyperexpression and recruitment of angiotensin-converting enzyme 2 (ACE2) and cellular transmembrane serine proteases (TMPRSSs), which are crucial for the virus internalization in affected cells.