PAPPA2 and preeclampsia: In contrast, our data are inconsistent with respect to the expression of PAPPA2, a regulator of trophoblast invasion and migration, or MNDA (myeloid cell nuclear differentiation antigen), which exhibited a lower expression level in our paradigms but is elevated in placentas from women with preeclampsia (Wagner et al., 2011; Kolialexi et al., 2017; Neuman et al., 2020).