FAT atypical cadherin 1 (FAT1) is a transmembrane protein, homologous to the tumor-suppressor genes fat and kujelei (also known as fat2) in Drosophila. By analyzing the TCGA database, (Martin et al., 2018) found that FAT1 shows a high-frequency mutation in many types of cancer. This evidence concerns the gene FAT1 and cancer.