In future studies, we will pay more attention to the NONHSAT101022.2–LMBRD2–β2-AR–NK Cell–IFN-γ axis, NONHSAT099004.2–miR-128-3p–ERG, MSTRG.85559.41–miR-150-5p–ITGB3 and MSTRG.34071.2–miR-146a-5p–FAXDC2 axes, MSTRG. 23249.3–ADAM10, and MSTRG.100048.9–IL-10 axes, which will help us to better understand the mechanism of these lncRNAs involved in the pathogenesis of SLE. Here, FAXDC2 is linked to systemic lupus erythematosus.