These results strongly suggest that NONHSAT101022.2 may be involved in the pathogenesis of SLE by regulating LMBRD2. LMBRD2 has a role in β2-adrenergic receptor (β2-AR) internalization, and knockdown of LMBRD2 by siRNA can enhance β2-AR signal transduction sevenfold on stimulation by isoproterenol (Paek et al., 2017). The gene discussed is LMBRD2; the disease is systemic lupus erythematosus.