Another work reported the activity of GAL isolated from Alpinia galanga rhizomes against promastigotes of L. (L.)donovani, the causal agent of visceral leishmaniasis, but the parasite inhibition was reached at 100 μM (IC50), (Kaur et al., 2010) almost twice the IC50 in L. amaz/tc3 determined in this work. This evidence concerns the gene GAL and visceral leishmaniasis.