Kaplan-Meier analysis of TCGA-LAML database consisting of 151 AML cases including 63 normal karyotypes, 10 inv(16), 7 t(8;21), 14 t(15;17), 7 t(11q23) and 50 other karyotypes showed that the lower expression of BDH1 correlated with the worse overall survival (OS, log-rank test, p=0.0417) in AML patients (Figure 2E). Here, BDH1 is linked to acute myeloid leukemia.