The results of GSEA showed that some cancer and tumor progression-related pathways (renal cell carcinoma, colorectal cancer, endometrial cancer, prostate cancer, ERBB signaling pathway, MAPK signaling pathway, WNT signaling pathway, and TGF-β signaling pathway) were enriched significantly in the high-risk group (Figures 7A, C). Here, TGFB1 is linked to Familial prostate cancer.