Specifically, TNFSF13B expression had close interactions with macrophage marker genes, namely, TLR and S100A9 genes; their receptor genes, TNFRSF13B and TNFRSF17, showed significant associations with the myeloma-related genes CD38, SDC1, and MYEOV (Figure 2B). Here, S100A9 is linked to plasma cell myeloma.