In the germination stage (2012–2013), rising terms included cancer cell, oxidative, mechanism, mitochondria, etc. While in the stable-growth stage (2014–2017), new terms contained more mechanism detection and pay more attention to different diseases, including lipid peroxidation, GPX4, glutathione, pathway, inflammation, resistance, molecule mechanism, Nrf2, disease, Parkinson’s disease, DNA damage, nuclear factor kappa-B (NF-κb), peroxidation, induction, etc. Notably, Nrf2 may have turning significance with a high centrality (41, 60). Here, GPX4 is linked to cancer.