The analysis of ADM expression according to genetic alteration of AML-related genes revealed no association with the mutational status of IDH1, IDH2, KRAS/NRAS, RUNX1, ASXL1, DNMT3A and TP53. Moreover, no significant differences were observed among ELN 2010 risk categories (Table 1). This evidence concerns the gene NRAS and acute myeloid leukemia.