Of note, some ADM co-expressed genes, including JUNB, CDKN1A, ANXA5, CYBB, NFKBIZ, that were upregulated in CD4+ T cells from AML patients compared with cells from healthy controls (Figure 5B), are known to participate to the Treg phenotype (65–69). The gene discussed is CD4; the disease is acute myeloid leukemia.