Conversely, we detected lower expression in FLT3-ITD AML (GSE6891, p = 0.023; TCGA-LAML, p = 0.001; GSE144468, p = 0.009) compared with FLT3-ITD-negative AML and in NPM1-mutated versus wild-type cases in the TCGA-LAML dataset (p = 0.034). This evidence concerns the gene NPM1 and acute myeloid leukemia.