reported, the outcome of IKZF1 deletion did not differ from that of IKZF1-WT patients both in pediatric and adult B-NEG ALL (B-ALL patients negative for the recurrent fusion transcripts, BCR-ABL, ETV6-RUNX1, TCF3-PBX1, KMT2A-rearrangement) (27). This evidence concerns the gene RUNX1 and acute lymphoblastic leukemia.