MUC16 and hepatocellular carcinoma: To analyze the impact of MUC16 on gene transcript levels in HCC cell lines, we adopted a high-throughput RNA-seq assay to assess HepG2 and Huh7 cells transfected with MUC16 siRNAs and NC-siRNA (HepG2-siRNA, HepG2-NC, Huh7-siRNA, and Huh7-NC.