To build the risk signature based on PVR-related genes for forecasting the OS of BLCA patients, we performed a LASSO Cox analysis on the basis of the 148 prognostic genes in the TCGA285 data set and it generated the LASSO risk signature which contained 6 PVR-related genes and corresponding coefficients (Figure 5A). The gene discussed is PVR; the disease is bladder transitional cell carcinoma.