SRC and breast cancer: Enhanced β-oxidation has been described in metastatic breast cancer (75, 181), and in metastatic triple negative breast cancer (TNBC) the knock down of carnitine palmitoyltransferases, important elements in the carnitine shuttle of fatty acids into the mitochondria, led to the inhibition of the c-Src proto-oncogene and Src-mediated metastasis (75, 94).