AKT SNPs are reported to be associated with susceptibility to various cancer types, such as nasopharyngeal carcinoma (NPC), OSCC, non-small cell lung cancer, pancreatic ductal adenocarcinoma, and GC via effects on protein expression and transcriptional activity (12, 36, 56, 58–60). This evidence concerns the gene AKT1 and non-small cell lung carcinoma.