In univariate analysis, lymph node metastasis (Hazard ratio = 1.43, 95% CI: 1.15–1.78, P = 0.001, Table 2) and FHL3 (Hazard ratio = 2.29, 95% CI: 1.45–3.63, P < 0.001, Table 2) were identified as risk factors of disease progression in GC. Here, FHL3 is linked to gastric cancer.