In this study, we examined the expression level of glucose 6-phosphate dehydrogenase (G6PD) and succinate dehydrogenase (SDH) in NSCLC via immunofluorescence assay; the examined metabolic enzymes, respectively involved in pentose phosphate pathway and mitochondrial function, displayed higher protein level in cancerous tissues than in paired para-carcinoma tissues (Figure 1). This evidence concerns the gene G6PD and carcinoma.