Disorders in cellular metabolism have been linked to the pathobiology of several common respiratory diseases and lung cancer (7); aberrantly activated pathways and genes, such as PI3K/Akt/mTOR, RAS/RAF and c-MYC, accelerate glucose and glutamine metabolism to meet the need of energy and building blocks for lung cancer proliferation, while abundant lactate accumulates due to anaerobic glycolysis (8). Here, MTOR is linked to lung cancer.