The validity of presepsin was evaluated in the diagnosis and follow up of sepsis in burn patients. A prospective study in a burn center included 37 patients. Presepsin, PCT, CRP and WBC levels were measured. Patients were classified as sepsis or non-sepsis according to the American Burn Association Consensus Criteria (ABA) 2007. The authors concluded that presepsin plasma levels had comparable performance in burn sepsis. This evidence concerns the gene CRP and Sepsis.