CRP and Sepsis: Presepsin and the biomarker sTREM-1 were more sensitive for the diagnosis of sepsis in the ICU compared to procalcitonin and CRP, with the most accurate indicator being a composite biomarker of presepsin and sTREM-1. In patients diagnosed with sepsis, higher values of both biomarkers were associated with mortality. A cutoff value of 1025 pg/ml presepsin had 83% specificity and 85% sensitivity for the diagnosis of sepsis.