Then we performed an IHC test on the greater omentum tissues to observe the expression of macrophages and discovered the higher CD86 expression while lower CD206 expression in the mice group that with PTX3 overexpression of gastric cancer cells compared with the control group (Fig. 6A, B), indicating that the up-regulation of the PTX3 in MFCs could inhibit the polarization to the M2 macrophages in the milky spot. Here, CD86 is linked to gastric cancer.