The expression of ApoM in cancer tissues and adjacent tissues is related to age (<50, P=0.010), gender (male, P=0.012), tumor size (P=0.020), necrosis (P=0.024) and liver cirrhosis (P=0.028), factors related to poor differentiation (P=0.0010) (Table 1). The gene discussed is APOM; the disease is cirrhosis of liver.