To investigate the role of CBP in ovarian cancer, two common ovarian cancer cell lines (HEY and SKOV3) were selected and infected with lentivirus harboring CBP shRNA (shCBP-1 and shCBP-2, respectively), and the control cells were infected with shRNA targeting firefly luciferase (shLuc). The gene discussed is CREBBP; the disease is ovarian cancer.