Additionally, the κ value of the PD-L1-positive expression rate was 0.771 (substantial) for the cutoff limit of ≥1%; the κ value for the cutoff limit of ≥50% could not be calculated because only one SCLC patient showed a high PD-L1 expression in either the EBUS-TBNA or TBB specimens. This evidence concerns the gene CD274 and small cell lung carcinoma.