Representative cases of immunohistochemical staining are shown in Figure 5A. Our results showed that in HCC patients with high MST4 expression, the levels of p-AKT, nuclear Snail1, and Ki67 are down-regulated, while the expression of E-cadherin is up-regulated in these patients (Figure 5A, 5B and Table 2). The gene discussed is MKI67; the disease is hepatocellular carcinoma.