Before PSM, albumin, INR, AST, ALT, AFP, HBV DNA, Edmondson grade, BCLC stage, ALBI score, PLR, NLR, capsule integrity, microvascular invasion, tumour embolus, tumour size, and SM were the possible influencing factors in the univariate analysis (P<0.05). The gene discussed is AFP; the disease is neoplasm.