SHMT2 and urinary bladder carcinoma: As expect, SHMT2 were highly upregulated in the four bladder carcinoma studies: Blaveri bladder, P = 1.79E-11; Dyrskjot bladder, P = 6.94E-10; Lee bladder, P = 3.19E-06; Sanchez-Carbayo bladder, P = 3.93E-17 (Dyrskjot et al., 2004; Blaveri et al., 2005; Sanchez-Carbayo et al., 2006; Lee et al., 2010; Figure 2A).