However, the prediction of the PD-associated genes targeted by miR-196a2 by TargetScanHuman revealed that miR-196a2-3p may target SYT11, MAPK1, MEF2C, IL12B, ATF6, IL7R, and CLU. The risk allele (C) of rs11614913 may therefore enhance the expression of miR-196a which, in turn, could affect the expression of its target genes and their related biological pathways involved in PD. The gene discussed is MAPK1; the disease is Parkinson disease.