Besides gene amplification of multiple m6A RNA methylation regulators in ovarian cancer, most of the m6A RNA methylation regulators exhibited upregulation at the RNA level in ovarian cancer such as METTL3, KIAA1429, HNRNPC, ZC3H13 as well as IGF2BP2, suggesting the critical unexplored functions of m6A RNA methylation in ovarian cancer. This evidence concerns the gene METTL3 and ovarian cancer.