The correlation analysis showed a significant positive correlation between the mRNA levels of OASL (r = 0.259, p = 0.030), MX1 (r = 0.255, p = 0.029), ISG15 (r = 0.242, p = 0.046), and LY6E (r = 0.250, p = 0.032) and SLEDAI-2K score in SLE patients. Here, ISG15 is linked to systemic lupus erythematosus.