No obvious cytotoxicity was observed, also no significant hemolysis. For BPTT treatments it was observed that necroptosis play an important role, mediating death process in cancer cells. These results were confirmed by the expression of necroptosis-related proteins, where it was observed a significantly expression of RIP1 and RIP3. Caspase-8 and Caspase-3 levels were not significantly changed. Here, CASP3 is linked to cancer.