In addition, CD3-CD56bright and CD3-CD56dim NK cells from ccRCC patients exhibited a substantially higher expression of CD45 (Figure 2J), while only CD3-CD56dim PBNK cells from ccRCC patients presented a higher frequency of PD-1+ cells (Figure 2K) without changes in the amount of PD-1 expression (not shown). The gene discussed is PTPRC; the disease is nonpapillary renal cell carcinoma.